On the Therapeutic Action of the Secale Cornutum

Observations on the Use of Secale Cornutum, (Ergot of Rye), in Cases of Tedious Labour

History of ergot alkaloids from ergotism to ergometrine.

Epidemics of ergotism occurred frequently in the Middle Ages. They were a source of inspiration for artists and were popularly known as 'St. Anthony's Fire', resulting in gangrene, neurological diseases and death. It was caused by eating rye bread contaminated with the fungus claviceps purpurea. In 1582 it was described that a delivery could be hastened by administering a few spurs of the secal...

Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice

In homeopathy, ability of ultra-high diluted drugs at or above potency 12C (diluted beyond Avogadro's limit) in ameliorating/curing various diseases is often questioned, particularly because the mechanism of action is not precisely known. We tested the hypothesis if suitable modulations of signal proteins could be one of the possible pathways of action of a highly diluted homeopathic drug, Seca...

Experimental Studies on the Relation of the Pituitary Body to Renal Function

1. The inconstant results of past observations on the relation of pituitary extracts to renal activity have been due chiefly to unsuitable methods. 2. A standard curve of artificially induced polyuria may be plotted for rabbits, giving 200 cc. of water by mouth. 3. Extracts of the pars intermedia and posterior lobe of the hypophysis, given by mouth, subcutaneously, or intravenously, are able de...

Probiotic Modes of Action and Its Effect on Biochemical Parameters and Growth Performance in Poultry

Provide a healthy diet is one of the major health challenges in the world to maintain health and nutritional status of populations. In this reason, new control strategies such as probiotics have been applied as prophylactic and therapeutic instead of antibiotics. In the same line, probiotics have antagonistic effects to various microorganisms proposed in several mechanisms including improvement...